BDBM50278563 1-(2-(6-fluoro-1-methylnaphthalen-2-yl)ethyl)piperazine::CHEMBL443090

SMILES Cc1c(CCN2CCNCC2)ccc2cc(F)ccc12

InChI Key InChIKey=KATOUFNMRLTTPE-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50278563   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278563(1-(2-(6-fluoro-1-methylnaphthalen-2-yl)ethyl)piper...)
Affinity DataIC50: 4nMAssay Description:Inhibition of radiolabeled serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50278563(1-(2-(6-fluoro-1-methylnaphthalen-2-yl)ethyl)piper...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of radiolabeled noradrenaline reuptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50278563(1-(2-(6-fluoro-1-methylnaphthalen-2-yl)ethyl)piper...)
Affinity DataKi:  1.01E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278563(1-(2-(6-fluoro-1-methylnaphthalen-2-yl)ethyl)piper...)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of radiolabeled dopamine reuptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed