BDBM50278562 1-(2-(6-fluoronaphthalen-2-yl)ethyl)piperazine::CHEMBL465515

SMILES Fc1ccc2cc(CCN3CCNCC3)ccc2c1

InChI Key InChIKey=AVSJNVNTDDYDEP-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50278562   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278562(1-(2-(6-fluoronaphthalen-2-yl)ethyl)piperazine | C...)
Affinity DataIC50: 11nMAssay Description:Inhibition of radiolabeled serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50278562(1-(2-(6-fluoronaphthalen-2-yl)ethyl)piperazine | C...)
Affinity DataKi:  8.50E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50278562(1-(2-(6-fluoronaphthalen-2-yl)ethyl)piperazine | C...)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of radiolabeled noradrenaline reuptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278562(1-(2-(6-fluoronaphthalen-2-yl)ethyl)piperazine | C...)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of radiolabeled dopamine reuptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed