BDBM50278560 (+/-)-4-(2-methoxy-1-(naphthalen-2-yloxy)ethyl)piperidine::CHEMBL471035

SMILES COCC(Oc1ccc2ccccc2c1)C1CCNCC1

InChI Key InChIKey=IMESNXOOQNBNMN-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50278560   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278560((+/-)-4-(2-methoxy-1-(naphthalen-2-yloxy)ethyl)pip...)
Affinity DataIC50: 5nMAssay Description:Inhibition of radiolabeled serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50278560((+/-)-4-(2-methoxy-1-(naphthalen-2-yloxy)ethyl)pip...)
Affinity DataIC50: 827nMAssay Description:Inhibition of radiolabeled noradrenaline reuptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278560((+/-)-4-(2-methoxy-1-(naphthalen-2-yloxy)ethyl)pip...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]granisetron from human 5HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed