BDBM50278559 7-(piperidin-4-ylmethoxy)-2-naphthonitrile::CHEMBL444985

SMILES N#Cc1ccc2ccc(OCC3CCNCC3)cc2c1

InChI Key InChIKey=ZINGRQZUIVEPKX-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50278559   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278559(7-(piperidin-4-ylmethoxy)-2-naphthonitrile | CHEMB...)
Affinity DataIC50: 3nMAssay Description:Inhibition of radiolabeled serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278559(7-(piperidin-4-ylmethoxy)-2-naphthonitrile | CHEMB...)
Affinity DataKi:  404nMAssay Description:Displacement of [3H]granisetron from human 5HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50278559(7-(piperidin-4-ylmethoxy)-2-naphthonitrile | CHEMB...)
Affinity DataKi:  3.50E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50278559(7-(piperidin-4-ylmethoxy)-2-naphthonitrile | CHEMB...)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of radiolabeled noradrenaline reuptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278559(7-(piperidin-4-ylmethoxy)-2-naphthonitrile | CHEMB...)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of radiolabeled dopamine reuptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed