BDBM50278528 CHEMBL4175393

SMILES Cc1c(sc2[nH]c(=O)n(O)c(=O)c12)C(O)=O

InChI Key InChIKey=YFJJZXZGDJNDNJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50278528   

TargetIntegrase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50278528(CHEMBL4175393)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of HIV1 integrase pre-incubated for 10 mins before DNA substrate addition and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2020
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50278528(CHEMBL4175393)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of polymerase activity of recombinant HIV1 reverse polymerase assessed as reduction in extension of an 18 nucleotide DNA primer using temp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2020
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50278528(CHEMBL4175393)
Affinity DataIC50: 100nMAssay Description:Inhibition of RNH activity of recombinant HIV1 reverse transcriptase RNase H assessed as reduction in internal cleavage of RNA strand using RNA/DNA d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2020
Entry Details Article
PubMed