BDBM50278525 (R)-6-(pyrrolidin-3-ylmethoxy)-2-naphthonitrile::CHEMBL506397

SMILES N#Cc1ccc2cc(OC[C@@H]3CCNC3)ccc2c1

InChI Key InChIKey=PYEILVKGQDUINV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50278525   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278525((R)-6-(pyrrolidin-3-ylmethoxy)-2-naphthonitrile | ...)
Affinity DataIC50: 42nMAssay Description:Inhibition of radiolabeled serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50278525((R)-6-(pyrrolidin-3-ylmethoxy)-2-naphthonitrile | ...)
Affinity DataIC50: 772nMAssay Description:Inhibition of radiolabeled noradrenaline reuptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed