BDBM50278515 CHEMBL470225::diethyl(4-(2-amino-5-(thiophen-2-yl)phenylcarbamoyl)benzylamino)methylphosphonate

SMILES CCOP(=O)(CNCc1ccc(cc1)C(=O)Nc1cc(ccc1N)-c1cccs1)OCC

InChI Key InChIKey=SDFJPCASBWGULI-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50278515   

TargetHistone deacetylase 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278515(diethyl(4-(2-amino-5-(thiophen-2-yl)phenylcarbamoy...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HDAC5More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278515(diethyl(4-(2-amino-5-(thiophen-2-yl)phenylcarbamoy...)
Affinity DataIC50: 14nMAssay Description:Inhibition of HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278515(diethyl(4-(2-amino-5-(thiophen-2-yl)phenylcarbamoy...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278515(diethyl(4-(2-amino-5-(thiophen-2-yl)phenylcarbamoy...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HDAC4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278515(diethyl(4-(2-amino-5-(thiophen-2-yl)phenylcarbamoy...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278515(diethyl(4-(2-amino-5-(thiophen-2-yl)phenylcarbamoy...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HDAC7More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278515(diethyl(4-(2-amino-5-(thiophen-2-yl)phenylcarbamoy...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of HDAC8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278515(diethyl(4-(2-amino-5-(thiophen-2-yl)phenylcarbamoy...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HDAC11More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50278515(diethyl(4-(2-amino-5-(thiophen-2-yl)phenylcarbamoy...)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed