BDBM50278510 CHEMBL4170599

SMILES ON1C(=O)Cc2cc(ccc2C1=O)-c1ccccc1

InChI Key InChIKey=MVZGKFIARDZTBZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50278510   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50278510(CHEMBL4170599)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of RNH activity of recombinant HIV1 reverse transcriptase RNase H assessed as reduction in internal cleavage of RNA strand using RNA/DNA d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2020
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50278510(CHEMBL4170599)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of polymerase activity of recombinant HIV1 reverse polymerase assessed as reduction in extension of an 18 nucleotide DNA primer using temp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50278510(CHEMBL4170599)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HIV1 integrase pre-incubated for 10 mins before DNA substrate addition and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2020
Entry Details Article
PubMed