BDBM50278430 (S)-3-(naphthalen-2-ylmethoxy)pyrrolidine::CHEMBL445794

SMILES C(O[C@H]1CCNC1)c1ccc2ccccc2c1

InChI Key InChIKey=IQZVBBALTJFFCB-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50278430   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278430((S)-3-(naphthalen-2-ylmethoxy)pyrrolidine | CHEMBL...)
Affinity DataIC50: 23nMAssay Description:Inhibition of radiolabeled serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50278430((S)-3-(naphthalen-2-ylmethoxy)pyrrolidine | CHEMBL...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of radiolabeled noradrenaline reuptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278430((S)-3-(naphthalen-2-ylmethoxy)pyrrolidine | CHEMBL...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of radiolabeled dopamine reuptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50278430((S)-3-(naphthalen-2-ylmethoxy)pyrrolidine | CHEMBL...)
Affinity DataKi:  1.57E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed