BDBM50278287 CHEMBL469381::N4-(2,3-dihydro-1H-inden-2-yl)-N6-(2-(dimethylamino)ethyl)pyrido[3,4-d]pyrimidine-4,6-diamine

SMILES CN(C)CCNc1cc2c(NC3Cc4ccccc4C3)ncnc2cn1

InChI Key InChIKey=FKZDWGCWJYVJIH-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278287   

TargetMetabotropic glutamate receptor 1(Rat)
Medical Research Council Technology

Curated by ChEMBL
LigandPNGBDBM50278287(N4-(2,3-dihydro-1H-inden-2-yl)-N6-(2-(dimethylamin...)
Affinity DataKi:  102nMAssay Description:Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of glutamate-evoked increase in calcium internalization preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed