BDBM50278207 CHEMBL4159674

SMILES Nc1cc(F)ccc1NC(=O)c1ccc(NC(=O)Cc2ccc(F)cc2)cc1

InChI Key InChIKey=DDUMZIDIZMKBIB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50278207   

TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50278207(CHEMBL4159674)
Affinity DataIC50: 200nMAssay Description:Inhibition of human HDAC3/NCOR2 using p53 (379 to 382 residues) derived fluorogenic peptide RHKKAcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50278207(CHEMBL4159674)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of human HDAC1 using p53 (379 to 382 residues) derived fluorogenic peptide RHKKAcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2020
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50278207(CHEMBL4159674)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human HDAC2 using p53 (379 to 382 residues) derived fluorogenic peptide RHKKAcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2020
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50278207(CHEMBL4159674)
Affinity DataIC50: 200nMAssay Description:Inhibition of full length human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 (395 to 489 residues) co-expressed in baculovirus infected sf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed