BDBM50278206 CHEMBL4172270

SMILES CC[C@@H](C(=O)Nc1ccc(cc1)C(=O)Nc1ccc(F)cc1N)c1ccccc1

InChI Key InChIKey=VLVGUAGNSVBLEP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50278206   

TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50278206(CHEMBL4172270)
Affinity DataIC50: 110nMAssay Description:Inhibition of human HDAC3/NCOR2 using p53 (379 to 382 residues) derived fluorogenic peptide RHKKAcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50278206(CHEMBL4172270)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human HDAC1 using p53 (379 to 382 residues) derived fluorogenic peptide RHKKAcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2020
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50278206(CHEMBL4172270)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human HDAC2 using p53 (379 to 382 residues) derived fluorogenic peptide RHKKAcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2020
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50278206(CHEMBL4172270)
Affinity DataIC50: 170nMAssay Description:Inhibition of full length human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 (395 to 489 residues) co-expressed in baculovirus infected sf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed