BDBM50278143 (S)-3,4-difluoro-N-(1-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)propan-2-yl)benzamide::CHEMBL511648

SMILES C[C@@H](CN1CCC2(CC1)N(CNC2=O)c1ccccc1)NC(=O)c1ccc(F)c(F)c1

InChI Key InChIKey=JMFQTTHZMGEEHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50278143   

TargetPhospholipase D1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50278143((S)-3,4-difluoro-N-(1-(4-oxo-1-phenyl-1,3,8-triaza...)
Affinity DataIC50: 150nMAssay Description:Inhibition of PLD1 in human Calu1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPhospholipase D2(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50278143((S)-3,4-difluoro-N-(1-(4-oxo-1-phenyl-1,3,8-triaza...)
Affinity DataIC50: 200nMAssay Description:Inhibition of GFP-labeled PLD2 in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed