BDBM50278141 (S)-N-(1-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)propan-2-yl)-2-naphthamide::CHEMBL471056

SMILES C[C@@H](CN1CCC2(CC1)N(CNC2=O)c1ccccc1)NC(=O)c1ccc2ccccc2c1

InChI Key InChIKey=KBMPJZSFOFZBQM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50278141   

TargetPhospholipase D1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50278141((S)-N-(1-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec...)
Affinity DataIC50: 25nMAssay Description:Inhibition of PLD1 in human Calu1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPhospholipase D2(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50278141((S)-N-(1-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec...)
Affinity DataIC50: 140nMAssay Description:Inhibition of GFP-labeled PLD2 in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPhospholipase D1(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50278141((S)-N-(1-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec...)
Affinity DataIC50: 25nMAssay Description:Inhibition of PLD1 in human calu1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetPhospholipase D2(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50278141((S)-N-(1-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human GST-tagged PLD2A in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed