BDBM50278103 (R)-(4-(1-amino-2-(2,4,5-trifluorophenyl)ethyl)piperidin-1-yl)(2,5-dimethylpyrimidin-4-yl)methanone::CHEMBL485123

SMILES Cc1ncc(C)c(n1)C(=O)N1CCC(CC1)[C@H](N)Cc1cc(F)c(F)cc1F

InChI Key InChIKey=AOIBZBXINYLQJL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50278103   

TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278103((R)-(4-(1-amino-2-(2,4,5-trifluorophenyl)ethyl)pip...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278103((R)-(4-(1-amino-2-(2,4,5-trifluorophenyl)ethyl)pip...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human DPP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50278103((R)-(4-(1-amino-2-(2,4,5-trifluorophenyl)ethyl)pip...)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of human ERG by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed