BDBM50278068 (S)-2-ethoxy-3-(7-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-4-yl)propanoic acid::CHEMBL519351

SMILES CCO[C@@H](Cc1ccc(OCCc2nc(oc2C)-c2ccccc2)c2sccc12)C(O)=O

InChI Key InChIKey=VPJCAJLVMQCQIC-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50278068   

TargetPeroxisome proliferator-activated receptor alpha(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50278068((S)-2-ethoxy-3-(7-(2-(5-methyl-2-phenyloxazol-4-yl...)
Affinity DataIC50: 333nMAssay Description:Displacement of radio labeled 2(S)-(2-benzoyl-phenylamino)-3-{4-[1,1-ditritio-2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-propionic acid from G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50278068((S)-2-ethoxy-3-(7-(2-(5-methyl-2-phenyloxazol-4-yl...)
Affinity DataIC50: 13nMAssay Description:Displacement of radio labeled 2(S)-(2-benzoyl-phenylamino)-3-{4-[1,1-ditritio-2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenyl}-propionic acid from G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50278068((S)-2-ethoxy-3-(7-(2-(5-methyl-2-phenyloxazol-4-yl...)
Affinity DataEC50:  58nMAssay Description:Agonist activity at human PPARalpha by luciferase reporter transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50278068((S)-2-ethoxy-3-(7-(2-(5-methyl-2-phenyloxazol-4-yl...)
Affinity DataEC50:  7nMAssay Description:Agonist activity at human PPARgamma expressed in BHK21 cells assessed as SEAP activity by luciferase reporter transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed