BDBM50277781 (2S)-2-[(2S)-2-[(5-ethoxy-1,2-oxazol-3-yl)formamido]-3-methoxypropanamido]-3-methoxy-N-[(2S)-1-[(2R)-2-methyloxiran-2-yl]-1-oxo-3-phenylpropan-2-yl]propanamide::CHEMBL489864

SMILES CCOc1cc(no1)C(=O)N[C@@H](COC)C(=O)N[C@@H](COC)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1

InChI Key InChIKey=VWQJDKOLBFDKEY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277781   

TargetProteasome subunit beta type-8(Human)
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277781((2S)-2-[(2S)-2-[(5-ethoxy-1,2-oxazol-3-yl)formamid...)
Affinity DataIC50: 5nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed