BDBM50277778 CHEMBL484002::N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)-1-((R)-2-methyloxiran-2-yl)-1-oxo-3-phenylpropan-2-ylamino)-1-oxopropan-2-ylamino)-1-oxopropan-2-yl)isoxazole-3-carboxamide

SMILES COC[C@H](NC(=O)[C@H](COC)NC(=O)c1ccon1)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1

InChI Key InChIKey=KVYCDMDHZNLNTN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277778   

TargetProteasome subunit beta type-8(Human)
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277778(N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)-1-((R)-2-...)
Affinity DataIC50: 93nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed