BDBM50277627 1-(5-tert-butyl-2-methoxyphenyl)-3-(naphthalen-1-yl)urea::CHEMBL482969

SMILES COc1ccc(cc1NC(=O)Nc1cccc2ccccc12)C(C)(C)C

InChI Key InChIKey=ICQWPUICUNPYEC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277627   

TargetMitogen-activated protein kinase 14(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277627(1-(5-tert-butyl-2-methoxyphenyl)-3-(naphthalen-1-y...)
Affinity DataIC50: 3.90E+3nMAssay Description:Binding affinity to p38alpha assessed as inhibition of ATF2 phosphorylation preincubated for 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed