BDBM50277387 CHEMBL4164091

SMILES Oc1cccc(CNCc2ccncc2)c1

InChI Key InChIKey=RSXSJMSASXLVOY-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50277387   

TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Emory University

Curated by ChEMBL

LigandBDBM50277387(CHEMBL4164091)Copy SMILESCopy InChI

Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at human GLUT4 expressed in HEK293 cells transfected with GLUT1 shRNA assessed as inhibition of [3H]2-deoxy-D-glucose uptake prei...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2020
Entry Details Article
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TargetSolute carrier family 2, facilitated glucose transporter member 8(Human)
Emory University

Curated by ChEMBL

LigandBDBM50277387(CHEMBL4164091)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human GLUT8 expressed in HEK293 cells transfected with GLUT1 shRNA assessed as inhibition of [3H]2-deoxy-D-glucose uptake prei...More data for this Ligand-Target Pair

Target InfoUniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
Emory University

Curated by ChEMBL

LigandBDBM50277387(CHEMBL4164091)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human GLUT1 expressed in HEK293 cells transfected with GLUT1 shRNA assessed as inhibition of [3H]2-deoxy-D-glucose uptake prei...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL