BDBM50277373 CHEMBL4165190

SMILES COc1ccc(CC(=O)N(Cc2ccncc2)Cc2cccc(OCCc3ccc(F)cc3)c2)cc1

InChI Key InChIKey=WLSXINVPTHYSNM-UHFFFAOYSA-N

Data  5 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50277373   

TargetSolute carrier family 2, facilitated glucose transporter member 14(Human)
Emory University

Curated by ChEMBL

LigandBDBM50277373(CHEMBL4165190)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human GLUT3 expressed in HEK293 cells transfected with GLUT1 shRNA assessed as inhibition of [3H]2-deoxy-D-glucose uptake prei...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2020
Entry Details Article
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TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
Emory University

Curated by ChEMBL

LigandBDBM50277373(CHEMBL4165190)Copy SMILESCopy InChI

Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of human GLUT1 in human KMS11 cells over-expressing human GLUT1 assessed as as inhibition of receptor-mediated cell proliferation after 72...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
Emory University

Curated by ChEMBL

LigandBDBM50277373(CHEMBL4165190)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human GLUT1 expressed in HEK293 cells transfected with GLUT1 shRNA assessed as inhibition of [3H]2-deoxy-D-glucose uptake prei...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Emory University

Curated by ChEMBL

LigandBDBM50277373(CHEMBL4165190)Copy SMILESCopy InChI

Affinity DataIC50: 1.82E+4nMAssay Description:Antagonist activity at human GLUT4 expressed in HEK293 cells transfected with GLUT1 shRNA assessed as inhibition of [3H]2-deoxy-D-glucose uptake prei...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2020
Entry Details Article
Copy Entry DOIPubMed
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TargetSolute carrier family 2, facilitated glucose transporter member 8(Human)
Emory University

Curated by ChEMBL

LigandBDBM50277373(CHEMBL4165190)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human GLUT8 expressed in HEK293 cells transfected with GLUT1 shRNA assessed as inhibition of [3H]2-deoxy-D-glucose uptake prei...More data for this Ligand-Target Pair

Target InfoUniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL