BDBM50277370 CHEMBL4171968

SMILES COc1ccc(cc1)C(=O)N(Cc1ccncc1)Cc1cccc(OCCc2ccc(F)cc2)c1

InChI Key InChIKey=KGDVHPZTXBPSIT-UHFFFAOYSA-N

Data  6 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50277370   

TargetSolute carrier family 2, facilitated glucose transporter member 1(Rat)
Emory University

Curated by ChEMBL

LigandBDBM50277370(CHEMBL4171968)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at rat C-terminal 6His/Myc-tagged GLUT1 assessed as reduction in 2-[3H]deoxyglucose uptake measured after 6 minsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetSolute carrier family 2, facilitated glucose transporter member 4(Human)
Emory University

Curated by ChEMBL

LigandBDBM50277370(CHEMBL4171968)Copy SMILESCopy InChI

Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity at human GLUT4 expressed in HEK293 cells transfected with GLUT1 shRNA assessed as inhibition of [3H]2-deoxy-D-glucose uptake prei...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetSolute carrier family 2, facilitated glucose transporter member 4(Rat)
Emory University

Curated by ChEMBL

LigandBDBM50277370(CHEMBL4171968)Copy SMILESCopy InChI

Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity at rat C-terminal 6His/Myc-tagged GLUT4 assessed as reduction in 2-[3H]deoxyglucose uptake measured after 6 minsMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetSolute carrier family 2, facilitated glucose transporter member 8(Human)
Emory University

Curated by ChEMBL

LigandBDBM50277370(CHEMBL4171968)Copy SMILESCopy InChI

Affinity DataIC50: 6.00E+3nMAssay Description:Antagonist activity at GLUT8 (unknown origin) assessed as reduction in 2-[3H]deoxyglucose uptake measured after 6 minsMore data for this Ligand-Target Pair

Target InfoUniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
Emory University

Curated by ChEMBL

LigandBDBM50277370(CHEMBL4171968)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human GLUT1 expressed in HEK293 cells transfected with GLUT1 shRNA assessed as inhibition of [3H]2-deoxy-D-glucose uptake prei...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetSolute carrier family 2, facilitated glucose transporter member 8(Human)
Emory University

Curated by ChEMBL

LigandBDBM50277370(CHEMBL4171968)Copy SMILESCopy InChI

Affinity DataIC50: 6.00E+3nMAssay Description:Antagonist activity at human GLUT8 expressed in HEK293 cells transfected with GLUT1 shRNA assessed as inhibition of [3H]2-deoxy-D-glucose uptake prei...More data for this Ligand-Target Pair

Target InfoUniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/2/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL