BDBM50277353 CHEMBL4170578

SMILES Nc1nc2[nH]c(CC(=O)Nc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cc2c(=O)[nH]1

InChI Key InChIKey=CETGJKHDVDGZDA-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277353   

TargetBifunctional purine biosynthesis protein ATIC/Thymidylate synthase/Trifunctional purine biosynthetic protein adenosine-3(Human)
Hebei Medical University

Curated by ChEMBL

LigandBDBM50277353(CHEMBL4170578)Copy SMILESCopy InChI

Affinity DataIC50: 7.5nMAssay Description:Inhibition of TS/AICARFTase/GARFTase in human KB cells assessed as reduction in cell proliferation in folate free medium after 72 hrs in presence of ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/1/2020
Entry Details Article
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