BDBM50277211 CHEMBL475090::N-cyclopropyl-4-(1-(2-(2,3-dihydro-1H-inden-2-yl)ethyl)piperidin-3-yl)pyrimidin-2-amine

SMILES C(CN1CCCC(C1)c1ccnc(NC2CC2)n1)C1Cc2ccccc2C1

InChI Key InChIKey=OTGGRKWIRVAPBH-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277211   

Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50277211(N-cyclopropyl-4-(1-(2-(2,3-dihydro-1H-inden-2-yl)e...)
Affinity DataEC50:  290nMAssay Description:Agonist activity at human 5HT1A receptor expressed in CHO cells by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50277211(N-cyclopropyl-4-(1-(2-(2,3-dihydro-1H-inden-2-yl)e...)
Affinity DataKi:  42.5nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed