BDBM50277148 (S)-2-amino-2-methyl-3-(4-(octyloxy)phenylamino)-3-oxopropyl dihydrogen phosphate::CHEMBL475495

SMILES CCCCCCCCOc1ccc(NC(=O)[C@@](C)(N)COP(O)(O)=O)cc1

InChI Key InChIKey=RNDGTSGYNDTFOA-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50277148   

TargetSphingosine 1-phosphate receptor 1(Human)
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277148((S)-2-amino-2-methyl-3-(4-(octyloxy)phenylamino)-3...)
Affinity DataIC50: 0.730nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277148((S)-2-amino-2-methyl-3-(4-(octyloxy)phenylamino)-3...)
Affinity DataIC50: 5.90nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277148((S)-2-amino-2-methyl-3-(4-(octyloxy)phenylamino)-3...)
Affinity DataIC50: 4nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277148((S)-2-amino-2-methyl-3-(4-(octyloxy)phenylamino)-3...)
Affinity DataIC50: 8.80nMAssay Description:Displacement of [33P]sphingosine-1-phosphate from human S1P5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277148((S)-2-amino-2-methyl-3-(4-(octyloxy)phenylamino)-3...)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at human S1P1 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Praecis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277148((S)-2-amino-2-methyl-3-(4-(octyloxy)phenylamino)-3...)
Affinity DataEC50:  16.3nMAssay Description:Agonist activity at human S1P3 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed