BDBM50277142 CHEMBL4161892

SMILES CN(C)c1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](NC(=O)[C@H](N)CSC(c2ccccc2)c2ccccc2)[C@H]1O

InChI Key InChIKey=KAYZHTXDZMMYRS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277142   

TargetPuromycin-sensitive aminopeptidase(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50277142(CHEMBL4161892)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of recombinant human N-terminal His6-MBP-tagged PSA expressed in Escherichia coli BL21 STAR (DE3) using 4-Ala-MNA as substrate measured fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50277142(CHEMBL4161892)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged APN (Lys69 to Lys967 residues) using Ala-AMC as substrate measured for 30 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed