BDBM50277117 (1S,16R)-13-(cyclopropylmethyl)-1,5,16-trimethyl-4,6,13-triazatetracyclo[10.3.1.0^{2,10}.0^{3,7}]hexadeca-2,4,7,9-tetraene::CHEMBL506290

SMILES C[C@H]1C2Cc3ccc4nc(C)[nH]c4c3[C@@]1(C)CCN2CC1CC1

InChI Key InChIKey=WNNMSXHAHUUIPN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50277117   

TargetKappa-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50277117((1S,16R)-13-(cyclopropylmethyl)-1,5,16-trimethyl-4...)
Affinity DataKi:  0.510nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50277117((1S,16R)-13-(cyclopropylmethyl)-1,5,16-trimethyl-4...)
Affinity DataKi:  2.5nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Rensselaer Polytechnic Institute

Curated by ChEMBL
LigandPNGBDBM50277117((1S,16R)-13-(cyclopropylmethyl)-1,5,16-trimethyl-4...)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]Naltrindole from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed