BDBM50277095 3-(5-(2-amino-1-methyl-1H-benzo[d]imidazol-4-yloxy)-1-oxoisoindolin-2-yl)propanoic acid::CHEMBL464398

SMILES Cn1c(N)nc2c(Oc3ccc4C(=O)N(CCC(O)=O)Cc4c3)cccc12

InChI Key InChIKey=FZSPARDKXKVYGG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50277095   

TargetIntegrin alpha-V(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50277095(3-(5-(2-amino-1-methyl-1H-benzo[d]imidazol-4-yloxy...)
Affinity DataIC50: 180nMAssay Description:Binding affinity to human integrin alphavbeta3 receptor by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-V(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50277095(3-(5-(2-amino-1-methyl-1H-benzo[d]imidazol-4-yloxy...)
Affinity DataIC50: 4.80E+3nMAssay Description:Binding affinity to human integrin alphavbeta5 receptor by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetIntegrin alpha-IIb(Human)
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50277095(3-(5-(2-amino-1-methyl-1H-benzo[d]imidazol-4-yloxy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to human integrin alpha2beta3 receptor by TRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed