BDBM50276954 CHEMBL4177457

SMILES CS(=O)(=O)c1nn(Cc2nc3cc(Cl)ccc3n2CC2COC2)c2cnccc12

InChI Key InChIKey=JCRHWUFAMLOIEZ-UHFFFAOYSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50276954   

TargetCytochrome P450 1A2(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50276954(CHEMBL4177457)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2020
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50276954(CHEMBL4177457)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50276954(CHEMBL4177457)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50276954(CHEMBL4177457)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50276954(CHEMBL4177457)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2020
Entry Details Article
PubMed
TargetFusion glycoprotein F0(Human respiratory syncytial virus)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50276954(CHEMBL4177457)
Affinity DataEC50:  5.40nMAssay Description:Inhibition of Respiratory syncytial virus Long fusion glycoprotein infected in Hep2 cells assessed as reduction in virus-induced cytopathic effect af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50276954(CHEMBL4177457)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2020
Entry Details Article
PubMed