BDBM50276581 (+/-)-wiedendiol B::CHEMBL456619

SMILES COc1ccc(O)c(O)c1\C=C1/[C@@H](C)CC[C@H]2C(C)(C)CCC[C@]12C

InChI Key InChIKey=SJKXQWZJYOQHJG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50276581   

TargetCholesteryl ester transfer protein(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50276581((+/-)-wiedendiol B | CHEMBL456619)
Affinity DataIC50: 5.00E+3nMAssay Description:Compound was tested for Cholesteryl ester transfer protein (CETP) inhibition by CETP-SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
UniversitäT Bayreuth

Curated by ChEMBL
LigandPNGBDBM50276581((+/-)-wiedendiol B | CHEMBL456619)
Affinity DataIC50: 700nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50276581((+/-)-wiedendiol B | CHEMBL456619)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of Cholesterol ester transfer protein (CETP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetCholesteryl ester transfer protein(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50276581((+/-)-wiedendiol B | CHEMBL456619)
Affinity DataIC50: 600nMAssay Description:Compound was tested for CETP inhibition by a precipitation method to separate lipoproteins after incubation of radiolabeled HDL with LDL and CETP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article