BDBM50276294 CHEMBL4161991

SMILES CCn1c(cc2cc(N\C(=C3/C(=O)Nc4cc(ccc34)C(=O)OC)c3ccccc3)ccc12)C(=O)N1CCN(C)CC1

InChI Key InChIKey=CEZCABCIQPGXGL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50276294   

TargetPlatelet-derived growth factor receptor beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276294(CHEMBL4161991)
Affinity DataIC50: 39nMAssay Description:Inhibition of N-terminal GST tagged human PDGFRbeta (557 to 1106 end residues) cytoplasmic domain expressed in baculovirus expression system preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50276294(CHEMBL4161991)
Affinity DataIC50: 105nMAssay Description:Inhibition of N-terminal biotinylated DYKDDDDK tagged human VEGFR2 (790 to 1356 end residues) cytoplasmic domain expressed in baculovirus expression ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2020
Entry Details Article
PubMed