BDBM50276280 3-(5-(4-chloro-3-ethylphenoxy)-2 -(3-(1,1,2,2-tetrafluoroethoxy)phenyl)-3,4-dihydroquinolin-1(2H)-yl)-1,1,1-trifluoropropan-2-ol::3-(5-(4-chloro-3-ethylphenoxy)-2-(3-(1,1,2,2-tetrafluoroethoxy)phenyl)-3,4-dihydroquinolin-1(2H)-yl)-1,1,1-trifluoropropan-2-ol::CHEMBL481069

SMILES CCc1cc(Oc2cccc3N(CC(O)C(F)(F)F)C(CCc23)c2cccc(OC(F)(F)C(F)F)c2)ccc1Cl

InChI Key InChIKey=KCELZBJBUMZXEK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50276280   

TargetCholesteryl ester transfer protein(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50276280(3-(5-(4-chloro-3-ethylphenoxy)-2-(3-(1,1,2,2-tetra...)
Affinity DataIC50: 400nMAssay Description:Inhibition of CETP-mediated transfer of [3H]cholesteryl ester from HDL donar particles to LDL acceptor particlesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50276280(3-(5-(4-chloro-3-ethylphenoxy)-2-(3-(1,1,2,2-tetra...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50276280(3-(5-(4-chloro-3-ethylphenoxy)-2-(3-(1,1,2,2-tetra...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human plasma derived CETPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed