BDBM50276097 CHEMBL4129902

SMILES COc1cc(ccc1Nc1ncc2c(n1)n(-c1cccc(NC(=O)C=C)c1)c(=O)n(C(C)C)c2=O)N(C)CCN(C)C

InChI Key InChIKey=JELNKXSFJXDCGG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50276097   

TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50276097(CHEMBL4129902)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R/T790M double mutant expressed in baculovirus expression system using Poly(Glu,Tyr)4:1 as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50276097(CHEMBL4129902)
Affinity DataIC50: 121nMAssay Description:Inhibition of recombinant human GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus expression system using Poly(Glu,Tyr)4:1 as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
East China University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50276097(CHEMBL4129902)
Affinity DataIC50: 982nMAssay Description:Inhibition of BTK (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed