BDBM50275973 CHEMBL4127869

SMILES CN(C)\N=C1\CN(CC(=O)Nc2cccc(c2)-c2cnn(C)c2)C(=O)C(Cc2c(C)cccc2C#N)CN1

InChI Key InChIKey=FYUSOWPRMPEAQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50275973   

TargetKallikrein-7(Mouse)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50275973(CHEMBL4127869)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of mouse KLK7 using MOCAcArg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2020
Entry Details Article
PubMed
TargetKallikrein-7(Human)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50275973(CHEMBL4127869)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged KLK7 (E23 to H252 residues) using MOCAcArg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2020
Entry Details Article
PubMed