BDBM50275972 CHEMBL4129899

SMILES COc1cc(Cl)ccc1CC1CN\C(CN(CC(=O)Nc2cccc(c2)-c2cnn(C)c2)C1=O)=N/N(C)C

InChI Key InChIKey=ZIDFBVMZIBEJJX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50275972   

TargetKallikrein-7(Mouse)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50275972(CHEMBL4129899)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of mouse KLK7 using MOCAcArg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2020
Entry Details Article
PubMed
TargetKallikrein-7(Human)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50275972(CHEMBL4129899)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged KLK7 (E23 to H252 residues) using MOCAcArg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2020
Entry Details Article
PubMed