BDBM50275971 CHEMBL4130204

SMILES COc1ccc(Cl)cc1C[C@@H]1CN\C(CN(CC(=O)Nc2cccc(c2)-c2cnn(C)c2)C1=O)=N/N(C)C

InChI Key InChIKey=WBBLXLACEVDRFZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50275971   

TargetKallikrein-7(Mouse)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50275971(CHEMBL4130204)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of mouse KLK7 using MOCAcArg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2020
Entry Details Article
PubMed
TargetKallikrein-7(Human)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50275971(CHEMBL4130204)
Affinity DataIC50: 520nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged KLK7 (E23 to H252 residues) using MOCAcArg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2020
Entry Details Article
PubMed
TargetKallikrein-5(Human)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50275971(CHEMBL4130204)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human KLK5 using Boc-Val-Pro-Arg-MCA as substrate preincubated for 10 mins followed by substrate addition measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTrypsin(Human)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50275971(CHEMBL4130204)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human trypsin using Boc-Gln-Ala-Arg-MCA as substrate preincubated for 10 mins followed by substrate addition measured after 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetKallikrein-7(Human)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50275971(CHEMBL4130204)
Affinity DataIC50: 520nMAssay Description:Inhibition of recombinant human KLK7 using MOCAc-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 10 mins followed by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed