BDBM50275902 CHEMBL525577::D-Phe-Gln-Trp-Ala-Val-b-Ala-His-Phe-Nle-NH2

SMILES CCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](C)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](N)Cc1ccccc1)C(C)C)C(N)=O

InChI Key InChIKey=GMEWMQLWXBFPOI-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50275902   

TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275902(D-Phe-Gln-Trp-Ala-Val-b-Ala-His-Phe-Nle-NH2 | CHEM...)
Affinity DataEC50:  3.90nMAssay Description:Agonist activity at recombinant BRS-3 receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization by FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin-releasing peptide receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275902(D-Phe-Gln-Trp-Ala-Val-b-Ala-His-Phe-Nle-NH2 | CHEM...)
Affinity DataEC50:  0.0600nMAssay Description:Agonist activity at recombinant gastrin releasing peptide receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuromedin-B receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275902(D-Phe-Gln-Trp-Ala-Val-b-Ala-His-Phe-Nle-NH2 | CHEM...)
Affinity DataEC50:  0.550nMAssay Description:Agonist activity at recombinant neuromedin B receptor expressed in baculovirus-transduced HEK293 cells assessed as intracellular calcium mobilization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275902(D-Phe-Gln-Trp-Ala-Val-b-Ala-His-Phe-Nle-NH2 | CHEM...)
Affinity DataKi:  0.360nMAssay Description:Binding affinity to BRS-3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGastrin-releasing peptide receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275902(D-Phe-Gln-Trp-Ala-Val-b-Ala-His-Phe-Nle-NH2 | CHEM...)
Affinity DataKi:  0.990nMAssay Description:Binding affinity to gastrin releasing peptide receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeuromedin-B receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275902(D-Phe-Gln-Trp-Ala-Val-b-Ala-His-Phe-Nle-NH2 | CHEM...)
Affinity DataKi:  8.90nMAssay Description:Binding affinity to neuromedin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed