BDBM50275827 CHEMBL472252::N-(2-amino-5-(1-methyl-1H-imidazol-4-yl)phenyl)-6-(2,8-diazaspiro[4.5]decan-8-yl)nicotinamide
SMILES Cn1cnc(c1)-c1ccc(N)c(NC(=O)c2ccc(nc2)N2CCC3(CCNC3)CC2)c1
InChI Key InChIKey=QNKFAFLRGQUIPR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50275827
Affinity DataIC50: 22nMAssay Description:Inhibition of human HDAC1 expressed in mammalian cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+7nMAssay Description:Inhibition of human HDAC3 expressed in mammalian cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 9.80E+3nMAssay Description:Displacement of [35S]MK499 from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
