BDBM50275756 4-(2-aminobenzo[d]thiazol-6-ylamino)-6-methyl-7-(2-(piperidin-1-yl)ethoxy)quinoline-3-carbonitrile::CHEMBL486370

SMILES Cc1cc2c(Nc3ccc4nc(N)sc4c3)c(cnc2cc1OCCN1CCCCC1)C#N

InChI Key InChIKey=HGSBSXZGQZUQQU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50275756   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50275756(4-(2-aminobenzo[d]thiazol-6-ylamino)-6-methyl-7-(2...)
Affinity DataIC50: 34.8nMAssay Description:Inhibition of cSrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50275756(4-(2-aminobenzo[d]thiazol-6-ylamino)-6-methyl-7-(2...)
Affinity DataIC50: 2.67E+4nMAssay Description:Inhibition of iNOS in mouse ANA1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50275756(4-(2-aminobenzo[d]thiazol-6-ylamino)-6-methyl-7-(2...)
Affinity DataIC50: 15nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Schering-Plough

Curated by ChEMBL
LigandPNGBDBM50275756(4-(2-aminobenzo[d]thiazol-6-ylamino)-6-methyl-7-(2...)
Affinity DataIC50: 3.13E+5nMAssay Description:Inhibition of iNOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed