BDBM50275625 5-methyl-N,7-diphenylimidazo[1,5-f][1,2,4]triazin-2-amine::CHEMBL487976

SMILES Cc1nc(-c2ccccc2)n2nc(Nc3ccccc3)ncc12

InChI Key InChIKey=VMVVGNPEKKNKGG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50275625   

TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275625(5-methyl-N,7-diphenylimidazo[1,5-f][1,2,4]triazin-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed