BDBM50275565 CHEMBL4125912

SMILES CCCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(O)=O)C(O)=O

InChI Key InChIKey=GXLJVDNMIVZEGB-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50275565   

TargetGlucagon-like peptide 1 receptor(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50275565(CHEMBL4125912)
Affinity DataEC50:  0.00640nMAssay Description:Agonist activity at human GLP1R expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2020
Entry Details Article
PubMed
TargetGlucagon-like peptide 1 receptor(Crab-eating macaque)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50275565(CHEMBL4125912)
Affinity DataEC50:  0.00410nMAssay Description:Agonist activity at monkey GLP1R expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2020
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50275565(CHEMBL4125912)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human glucagon receptor expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2020
Entry Details Article
PubMed
TargetGastric inhibitory polypeptide receptor(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50275565(CHEMBL4125912)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GIP receptor expressed in HEK293 cells assessed as cAMP accumulation after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2020
Entry Details Article
PubMed