BDBM50275501 4-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(3-methoxypropyl)-1H-benzo[d]imidazol-2-yl)benzamide::CHEMBL486757

SMILES COCCCn1c(NC(=O)c2ccc(cc2)C#N)nc2cc(CN(C)C3CCCCC3)ccc12

InChI Key InChIKey=HOWZJLASEFUNIW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50275501   

TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275501(4-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50: 46nMAssay Description:Inhibition of ITK by DELPHIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275501(4-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275501(4-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275501(4-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275501(4-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50275501(4-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed