BDBM50275347 4-(5-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-2-(2-(pyridin-4-yl)ethylamino)pyrimidin-4-ylamino)phenol::CHEMBL486949

SMILES Oc1ccc(Nc2nc(NCCc3ccncc3)ncc2-c2nnc(o2)C2CC2)cc1

InChI Key InChIKey=PBPZCBWBEMJSBP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50275347   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandPNGBDBM50275347(4-(5-(5-cyclopropyl-1,3,4-oxadiazol-2-yl)-2-(2-(py...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of GST-tagged FLT3 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed