BDBM50275281 CHEMBL487360::cis-1-(4-(3-methoxyphenyl)cyclohexyl)-4-(naphthalen-1-yl)piperazine

SMILES COc1cccc(c1)[C@@H]1CC[C@@H](CC1)N1CCN(CC1)c1cccc2ccccc12

InChI Key InChIKey=RBBSEEBITXSZAO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50275281   

Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Guinea pig)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50275281(cis-1-(4-(3-methoxyphenyl)cyclohexyl)-4-(naphthale...)
Affinity DataKi:  17nMAssay Description:Displacement of [3H](-)-(S)-emopamil from EBP in guinea pig liver membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50275281(cis-1-(4-(3-methoxyphenyl)cyclohexyl)-4-(naphthale...)
Affinity DataKi:  74nMAssay Description:Displacement of [3H]8OH-DPAT from 5HT1A receptor in rat hippocampal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50275281(cis-1-(4-(3-methoxyphenyl)cyclohexyl)-4-(naphthale...)
Affinity DataKi:  240nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane without cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Universita Degli Studi Di Bari

Curated by ChEMBL
LigandPNGBDBM50275281(cis-1-(4-(3-methoxyphenyl)cyclohexyl)-4-(naphthale...)
Affinity DataKi:  1.31E+3nMAssay Description:Displacement of [3H]spiroperidol from dopamine D2 receptor in rat striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed