BDBM50275263 3-(dimethylamino) butyl pyrrolidine-1-carboxylate::CHEMBL486573

SMILES CC(CCOC(=O)N1CCCC1)N(C)C

InChI Key InChIKey=SZRTUTRKBGEAFX-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50275263   

LigandPNGBDBM50275263(3-(dimethylamino) butyl pyrrolidine-1-carboxylate ...)
Affinity DataEC50:  7.10E+3nMAssay Description:Agonist activity at mouse neuronal acetylcholine receptor subunit alpha4beta2 expressed in HEK293T cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50275263(3-(dimethylamino) butyl pyrrolidine-1-carboxylate ...)
Affinity DataKi:  200nMAssay Description:Displacement of [3H]epibatidine from rat recombinant alpha4beta2 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50275263(3-(dimethylamino) butyl pyrrolidine-1-carboxylate ...)
Affinity DataKi:  2.20E+3nMAssay Description:Displacement of [3H]epibatidine from rat recombinant alpha-4-beta-4 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50275263(3-(dimethylamino) butyl pyrrolidine-1-carboxylate ...)
Affinity DataKi:  2.50E+4nMAssay Description:Displacement of [3H]epibatidine from rat recombinant alpha-3-beta-4 nAChR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50275263(3-(dimethylamino) butyl pyrrolidine-1-carboxylate ...)
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]MLA from rat alpha-7 nAChR/mouse 5HT3A chimera expressed in human tsA-201 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed