BDBM50275186 CHEMBL4128971

SMILES CC(C)C[C@H](NC(=O)NCc1cn(Cc2cccc(OCc3ccccc3)c2)nn1)C(=O)NO

InChI Key InChIKey=HWJCWGXHJDEXFW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50275186   

TargetAminopeptidase N(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50275186(CHEMBL4128971)
Affinity DataIC50: 870nMAssay Description:Inhibition of APN in human ES2 cells using L-Leu-pnitroanilide as substrate pretreated for 5 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2020
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50275186(CHEMBL4128971)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of APN in human PLC/PRF/5 cells using L-Leu-pnitroanilide as substrate pretreated for 5 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2020
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50275186(CHEMBL4128971)
Affinity DataIC50: 240nMAssay Description:Inhibition of APN in porcine kidney microsomes using L-Leu-pnitroanilide as substrate pretreated for 5 mins followed by substrate addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2020
Entry Details Article
PubMed