BDBM50275141 CHEMBL4127457

SMILES COc1ccccc1C(C)n1cc(CNC(=O)N[C@@H](CC(C)C)C(=O)NO)nn1

InChI Key InChIKey=XYTMRDRBLGUEDP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50275141   

TargetAminopeptidase N(Pig)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50275141(CHEMBL4127457)
Affinity DataIC50: 550nMAssay Description:Inhibition of APN in porcine kidney microsomes using L-Leu-pnitroanilide as substrate pretreated for 5 mins followed by substrate addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2020
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50275141(CHEMBL4127457)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of APN in human ES2 cells using L-Leu-pnitroanilide as substrate pretreated for 5 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2020
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50275141(CHEMBL4127457)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of APN in human PLC/PRF/5 cells using L-Leu-pnitroanilide as substrate pretreated for 5 mins followed by substrate addition measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2020
Entry Details Article
PubMed