BDBM50275003 CHEMBL4126256

SMILES OC(=O)CNC(=O)c1ncc(cc1O)-c1cn(CCOc2ccc(Cl)cc2)nn1

InChI Key InChIKey=FKUAGIKRPHJIJN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50275003   

TargetEgl nine homolog 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50275003(CHEMBL4126256)
Affinity DataIC50: 6.43E+3nMAssay Description:Inhibition of HIF-PHD2 (181 to 426 residues) (unknown origin) using HIF1-alpha (556 to 574 residues) as substrate in presence of 2-OG preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50275003(CHEMBL4126256)
Affinity DataIC50: 80nMAssay Description:Inhibition of HIF-PHD2 (181 to 426 residues) (unknown origin) using FITC-HIF1-alpha (556 to 574 residues) as substrate after 60 mins by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50275003(CHEMBL4126256)
Affinity DataIC50: 77nMAssay Description:Inhibition of PHD2 (181 to 426 residues) (unknown origin) using FITC-HIF1alpha (556 to 574 residues) as substrate after 60 mins by fluorescence polar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed