BDBM50274678 CHEMBL485553::N,N-dimethyl-2-(2-(4-(4-methylpiperazin-1-yl)phenyl)quinazolin-4-yloxy)ethanamine

SMILES CN(C)CCOc1nc(nc2ccccc12)-c1ccc(cc1)N1CCN(C)CC1

InChI Key InChIKey=AVZWCYTVUMJYQE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274678   

TargetToll-like receptor 9(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50274678(N,N-dimethyl-2-(2-(4-(4-methylpiperazin-1-yl)pheny...)
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity at human TLR9 expressed in HEK293 cells assessed as blockade of CpG oligonucleotide-induced immune response by NF-kappaB lucifera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed