BDBM50274676 CHEMBL4125955

SMILES C[C@@H](C1CC1)N1Cc2cc(cc(Cl)c2C1=O)-c1cc(NC(C)=O)no1

InChI Key InChIKey=ALHYYNUQHJPBGH-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50274676   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Pharmaron-Beijing

Curated by ChEMBL

LigandBDBM50274676(CHEMBL4125955)Copy SMILESCopy InChI

Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant human 6His-tagged PI3Kgamma (144 to 1102 residues) using DiC8-PIP2 as substrate preincubated for 10 mins followed by substr...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/13/2020
Entry Details Article
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Pharmaron-Beijing

Curated by ChEMBL

LigandBDBM50274676(CHEMBL4125955)Copy SMILESCopy InChI

Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of recombinant human 6His-tagged PI3K p110alpha/p85alpha using DiC8-PIP2 as substrate preincubated for 10 mins followed by substrate addit...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/13/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL